Ulcerative colitis

Ulcerative colitis is a chronic inflammatory bowel disease of unknown cause.

Symptoms include abdominal pain, diarrhea, blood in stool, fever, weight loss and anemia. Standard treatment includes anti-inflammatory, immunosuppressive and biological drugs.

For patients not responding to medical therapy, surgical removal of the large intestine is often the only remaining treatment option.

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Kappaproct

Kappaproct is a potential new medication for patients with severe ulcerative colitis.

Kappaproct is a first in class treatment that provides a local anti-inflammatory effect, leading to healing of the mucosa and improvement of clinical symptoms.

Kappaproct has very limited systemic absorption. This gives the drug a favorable safety profile, in sharp contrast to many approved treatments.

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